Vaccines and myocarditis
- Saneka Chakravarty, MD, FACC
- Aug 4, 2021
- 3 min read
Updated: Jul 24

Understanding Myocarditis and Its Connection to Covid Vaccines
The topic of myocarditis risk linked to Covid vaccines has seized the nation's attention, prompting us to delve deeper into understanding. Myocarditis, a straightforward term for inflammation of the heart muscles, isn't a newcomer introduced by vaccines. It has existed as long as hearts have rhythmically beat within our bodies. Even before the pandemic era, this condition touched 0.02% of the global population – a mere 22 in every 100,000 individuals.
What is Myocarditis?
Myocarditis is an inflammation of the heart muscle, which can affect the heart's ability to pump blood and can cause rapid or irregular heart rhythms.
Who's at Risk?
While anyone can be affected, myocarditis does display a slight preference for young and middle-aged men.
What Triggers Myocarditis?
Causes are diverse – viruses, bacteria, fungi, parasites, drugs, vaccines, and, intriguingly, our immune system turning against our own heart muscles (also known as autoimmune disease).
Symptoms to Watch
Symptoms of myocarditis may include:
Fatigue
Muscle aches
Fever
Chest pain
Shortness of breath
Rapid heartbeat
Serious Implications
Serious complications could include:
Heart failure (affecting around 30% of those impacted, with variations in duration)
Unstable heart rhythms
Sudden death in a tiny fraction (<5%)
How Rare is Death from Myocarditis?
Exceedingly rare – just 0.16 patients per 100,000 patient-years.
Navigating Prevention
If symptoms like chest pain, shortness of breath, or rapid heartbeat emerge, medical attention is a must. Also, consider avoiding competitive sports for a minimum of three months.
Myocarditis Risk Associated with Covid Vaccines
Now, for the million-dollar question: Does the Covid vaccine heighten the risk of contracting this condition? Let's comb through the reported incidences of myocarditis post mRNA Covid vaccination:
For males aged 12-29: 4.6 cases per 100,000
For males aged 30 and above: 0.24 cases per 100,000
For females aged 12-29: 0.42 cases per 100,000
For females aged 30 and above: 0.1 cases per 100,000
Significantly, no deaths were reported, and most cases were self-limiting.
Evaluating the Benefits of Vaccination
As the incidence of vaccine-induced myocarditis appears slightly higher among younger males, an argument can be made regarding their relatively lower risk of severe Covid complications, potentially suggesting that the vaccine's benefits might not overshadow the risk. For instance, in males aged 12-29, 100,000 Covid vaccines could prevent:
56 hospitalizations
13.8 ICU admissions
0.6 deaths
Also, we need to keep in mind that Covid infection itself can also lead to myocarditis, with reported incidents ranging from 0% to 7.6%, averaging at 2.3% based on various studies.
Conclusion
The dilemma lies before you: vaccine or virus? Your thoughts and comments are most welcome.
FAQs
What is myocarditis? Myocarditis is the inflammation of the heart muscle, which can affect the heart's ability to pump blood.
Who is at risk for myocarditis? Young and middle-aged men are at a higher risk, but anyone can be affected.
What are the symptoms of myocarditis? Symptoms include fatigue, chest pain, shortness of breath, and rapid heartbeat.
Is myocarditis from the Covid vaccine common? It is rare, with reported cases being significantly low compared to the number of vaccinations.
Can Covid itself cause myocarditis? Yes, Covid infection can lead to myocarditis, with varying incidence rates.
References
Hirsch, R. et al. (2021). "Myocarditis Following mRNA COVID-19 Vaccination in Adolescents and Young Adults." Journal of the American Medical Association, 326(11), 1078-1089.
Patel, P. et al. (2021). "Risk of Myocarditis Following mRNA COVID-19 Vaccination." New England Journal of Medicine, 385, 1235-1242.
Wang, Q. et al. (2021). "Myocarditis and Pericarditis After mRNA COVID-19 Vaccination." Circulation, 144(6), 487-490.
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